Mice at RISE

Summary

Key Points

• —The facility never lifts mice by the tail or with tweezers, using cupped hands or a gentle tongue instead. 0:31
• —Initial handling sessions aim to create trust between the mouse and handler, allowing the mouse to become comfortable with the handler’s hands and the vet bed. 0:48
• —Mice that are shy may need extra time before they willingly enter the handler’s hand. 1:21
• —Observation boxes are used to continuously monitor mouse behavior during training and study periods, providing data on general condition. 2:32
• —Gentle handling and training enable mice to be calmly blood‑sampled from the saphenous vein without a restrainer, even when multiple mice are processed together. 3:42
• —After procedures, mice often seek contact with the handler, indicating reduced stress and successful habituation. 4:11
• —Intravenous dosing can be performed on trained mice while they remain calm and observant, allowing easy detection of substance‑related symptoms. 4:35
• —Micro‑sampling is prioritized, and soft incubators may be used post‑procedure to support recovery. 5:15
• —Clicker training teaches mice to perform tasks such as placing a pellet and chewing a stick, demonstrating their memory can last up to a month. 5:46
• —The video encourages researchers to adopt these refinement techniques to improve mouse welfare and invites contact for further information. 6:08